Cargando…

4-Methoxydalbergione suppresses growth and induces apoptosis in human osteosarcoma cells in vitro and in vivo xenograft model through down-regulation of the JAK2/STAT3 pathway

Although the heartwood of Dalbergia odorifera T. Chen (Leguminosae) is an important source of traditional Korean and Chinese medicines, the effects of novel compound methoxydalbergione (4-MD) isolated from Dalbergia odorifera was not reported. Herein, we investigated the effects of the 4-MD in vitro...

Descripción completa

Detalles Bibliográficos
Autores principales: Park, Kyung-Ran, Yun, Hyung-Mun, Quang, Tran-Hong, Oh, Hyuncheol, Lee, Dong-Sung, Auh, Q-Schick, Kim, Eun-Cheol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872761/
https://www.ncbi.nlm.nih.gov/pubmed/26755649
http://dx.doi.org/10.18632/oncotarget.6873