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Cdk3-promoted epithelial-mesenchymal transition through activating AP-1 is involved in colorectal cancer metastasis

Cyclin dependent kinase-3 (Cdk3) is a positive regulator of the G1 mammalian cell cycle phase. Cdk3 is involved in cancer progression, but very little is known about its mechanism in cancer development and progression. Herein, we found that Cdk3 increased colorectal cancer metastasis through promoti...

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Detalles Bibliográficos
Autores principales: Lu, Jinping, Zhang, Zhen Lin, Huang, Damao, Tang, Na, Li, Yuejin, Peng, Zhengke, Lu, Chengrong, Dong, Zigang, Tang, Faqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872765/
https://www.ncbi.nlm.nih.gov/pubmed/26755651
http://dx.doi.org/10.18632/oncotarget.6875