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Survivin inhibitor YM155 suppresses gastric cancer xenograft growth in mice without affecting normal tissues

Survivin overexpression is associated with poor prognosis of human gastric cancer, and is a target for gastric cancer therapy. YM155 is originally identified as a specific inhibitor of survivin. In this study, we investigated the antitumor effect of YM155 on human gastric cancer. Our results showed...

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Detalles Bibliográficos
Autores principales: Cheng, Xiao Jiao, Lin, Jia Cheng, Ding, Yan Fei, Zhu, Liming, Ye, Jing, Tu, Shui Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872771/
https://www.ncbi.nlm.nih.gov/pubmed/26771139
http://dx.doi.org/10.18632/oncotarget.6898