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The probiotic Propionibacterium freudenreichii as a new adjuvant for TRAIL-based therapy in colorectal cancer

TNF-Related Apoptosis-Inducing Ligand (TRAIL) is a well-known apoptosis inducer, which activates the extrinsic death pathway. TRAIL is pro-apoptotic on colon cancer cells, while not cytotoxic towards normal healthy cells. However, its clinical use is limited by cell resistance to cell death which oc...

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Detalles Bibliográficos
Autores principales: Cousin, Fabien J., Jouan-Lanhouet, Sandrine, Théret, Nathalie, Brenner, Catherine, Jouan, Elodie, Le Moigne-Muller, Gwénaëlle, Dimanche-Boitrel, Marie-Thérèse, Jan, Gwénaël
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872776/
https://www.ncbi.nlm.nih.gov/pubmed/26771233
http://dx.doi.org/10.18632/oncotarget.6881