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TRAF6 regulates melanoma invasion and metastasis through ubiquitination of Basigin

TRAF6 plays a crucial role in the regulation of the innate and adaptive immune responses. Although studies have shown that TRAF6 has oncogenic activity, the role of TRAF6 in melanoma is unclear. Here, we report that TRAF6 is overexpressed in primary as well as metastatic melanoma tumors and melanoma...

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Detalles Bibliográficos
Autores principales: Luo, Zhongling, Zhang, Xu, Zeng, Weiqi, Su, Juan, Yang, Keda, Lu, Lixia, Lim, Chuan Bian, Tang, Wen, Wu, Lisha, Zhao, Shuang, Jia, Xuekun, Peng, Cong, Chen, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872777/
https://www.ncbi.nlm.nih.gov/pubmed/26769849
http://dx.doi.org/10.18632/oncotarget.6886