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A novel nuclear Src and p300 signaling axis controls migratory and invasive behavior in pancreatic cancer

The presence of Src in the nuclear compartment has been previously reported, although its significance has remained largely unknown. We sought to delineate the functions of the nuclear pool of Src within the context of malignant progression. Active Src is localized within the nuclei of human pancrea...

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Detalles Bibliográficos
Autores principales: Paladino, David, Yue, Peibin, Furuya, Hideki, Acoba, Jared, Rosser, Charles J., Turkson, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872783/
https://www.ncbi.nlm.nih.gov/pubmed/26695438
http://dx.doi.org/10.18632/oncotarget.6635