Crosstalk between ATF4 and MTA1/HDAC1 promotes osteosarcoma progression

The stress response gene activating transcription factor 4 (ATF4) is involved in metastatic behavior and cellular protection. Here we show that ATF4 is upregulated in osteosarcoma (OS) cell lines and patient clinical samples as compared to matched non-tumor tissue. Overexpression of ATF4 in OS cells...

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Detalles Bibliográficos
Autores principales: Zeng, Heng, Zhang, Jin-ming, Du, Yu, Wang, Jiang, Ren, Ye, Li, Mi, Li, Hao, Cai, Zhuo, Chu, Qian, Yang, Caihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872789/
https://www.ncbi.nlm.nih.gov/pubmed/26797758
http://dx.doi.org/10.18632/oncotarget.6940

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872789/
https://www.ncbi.nlm.nih.gov/pubmed/26797758
http://dx.doi.org/10.18632/oncotarget.6940

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