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CXCR6-CXCL16 axis promotes prostate cancer by mediating cytoskeleton rearrangement via Ezrin activation and α(v)β(3) integrin clustering

Cytoskeletal rearrangement is required for migration and invasion, which are the key steps of cancer metastasis. Ezrin and integrin co-ordinate these processes by regulating cellular adhesion and cytoskeletal polymerization-depolymerization. It is also well established that chemokine-chemokine recep...

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Detalles Bibliográficos
Autores principales: Singh, Rajesh, Kapur, Neeraj, Mir, Hina, Singh, Nalinaksha, Lillard, James W., Singh, Shailesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872790/
https://www.ncbi.nlm.nih.gov/pubmed/26799186
http://dx.doi.org/10.18632/oncotarget.6944