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Comparison of liver oncogenic potential among human RAS isoforms

Mutation in one of three RAS genes (i.e., HRAS, KRAS, and NRAS) leading to constitutive activation of RAS signaling pathways is considered a key oncogenic event in human carcinogenesis. Whether activated RAS isoforms possess different oncogenic potentials remains an unresolved question. Here, we com...

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Detalles Bibliográficos
Autores principales: Chung, Sook In, Moon, Hyuk, Ju, Hye-Lim, Kim, Dae Yeong, Cho, Kyung Joo, Ribback, Silvia, Dombrowski, Frank, Calvisi, Diego F., Ro, Simon Weonsang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872791/
https://www.ncbi.nlm.nih.gov/pubmed/26799184
http://dx.doi.org/10.18632/oncotarget.6931