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Comparison of Antibodies with Amylase Activity from Cerebrospinal Fluid and Serum of Patients with Multiple Sclerosis

We have recently shown that IgGs from serum and cerebrospinal fluid (CSF) of MS patients are active in hydrolysis of DNA and myelin basic protein. According to literature data, anti-DNA and anti-MBP abzymes may promote important neuropathologic mechanisms in this chronic inflammatory disorder and in...

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Detalles Bibliográficos
Autores principales: Doronin, Vasilii B., Parkhomenko, Taisiya A., Castellazzi, Massimiliano, Cesnik, Edward, Buneva, Valentina N., Granieri, Enrico, Nevinsky, Georgy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873009/
https://www.ncbi.nlm.nih.gov/pubmed/27196086
http://dx.doi.org/10.1371/journal.pone.0154688