Cargando…

An Integrated Data Driven Approach to Drug Repositioning Using Gene-Disease Associations

Drug development is both increasing in cost whilst decreasing in productivity. There is a general acceptance that the current paradigm of R&D needs to change. One alternative approach is drug repositioning. With target-based approaches utilised heavily in the field of drug discovery, it becomes...

Descripción completa

Detalles Bibliográficos
Autores principales: Mullen, Joseph, Cockell, Simon J., Woollard, Peter, Wipat, Anil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873016/
https://www.ncbi.nlm.nih.gov/pubmed/27196054
http://dx.doi.org/10.1371/journal.pone.0155811