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An Integrated Data Driven Approach to Drug Repositioning Using Gene-Disease Associations
Drug development is both increasing in cost whilst decreasing in productivity. There is a general acceptance that the current paradigm of R&D needs to change. One alternative approach is drug repositioning. With target-based approaches utilised heavily in the field of drug discovery, it becomes...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873016/ https://www.ncbi.nlm.nih.gov/pubmed/27196054 http://dx.doi.org/10.1371/journal.pone.0155811 |