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Nanofiber Alignment Regulates NIH3T3 Cell Orientation and Cytoskeletal Gene Expression on Electrospun PCL+Gelatin Nanofibers

To examine the influence of substrate topology on the behavior of fibroblasts, tissue engineering scaffolds were electrospun from polycaprolactone (PCL) and a blend of PCL and gelatin (PCL+Gel) to produce matrices with both random and aligned nanofibrous orientations. The addition of gelatin to the...

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Detalles Bibliográficos
Autores principales: Fee, Timothy, Surianarayanan, Swetha, Downs, Crawford, Zhou, Yong, Berry, Joel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873125/
https://www.ncbi.nlm.nih.gov/pubmed/27196306
http://dx.doi.org/10.1371/journal.pone.0154806