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Quantitative Contribution of IL2Rγ to the Dynamic Formation of IL2-IL2R Complexes

Interleukin-2 (IL2) is a growth factor for several immune cells and its function depends on its binding to IL2Rs in the cell membrane. The most accepted model for the assembling of IL2-IL2R complexes in the cell membrane is the Affinity Conversion Model (ACM). This model postulates that IL2R recepto...

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Detalles Bibliográficos
Autores principales: Ponce, Luis F., García-Martínez, Karina, León, Kalet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873224/
https://www.ncbi.nlm.nih.gov/pubmed/27195783
http://dx.doi.org/10.1371/journal.pone.0155684