Ubiquitylation of Rad51d Mediated by E3 Ligase Rnf138 Promotes the Homologous Recombination Repair Pathway

Ubiquitylation has an important role as a signal transducer that regulates protein function, subcellular localization, or stability during the DNA damage response. In this study, we show that Ring domain E3 ubiquitin ligases RNF138 is recruited to DNA damage site quickly. And the recruitment is medi...

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Detalles Bibliográficos
Autores principales: Han, Deqiang, Liang, Junbo, Lu, Yalan, Xu, Longchang, Miao, Shiying, Lu, Lin-Yu, Song, Wei, Wang, Linfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873259/
https://www.ncbi.nlm.nih.gov/pubmed/27195665
http://dx.doi.org/10.1371/journal.pone.0155476

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873259/
https://www.ncbi.nlm.nih.gov/pubmed/27195665
http://dx.doi.org/10.1371/journal.pone.0155476

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