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Mycobacterium tuberculosis induces the miR-33 locus to reprogram autophagy and host lipid metabolism
Mycobacterium tuberculosis (Mtb) survives within macrophages by evading delivery to the lysosome and promoting the accumulation of lipid bodies, which serve as a bacterial source of nutrients. Here we show that by inducing miR-33 and its passenger strand miR-33*, Mtb inhibits integrated pathways inv...
| Autores principales: | , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873392/ https://www.ncbi.nlm.nih.gov/pubmed/27089382 http://dx.doi.org/10.1038/ni.3434 |