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Atypical role of sprouty in p21 dependent inhibition of cell proliferation in colorectal cancer

Sprouty (SPRY) appears to act as a tumor suppressor in cancer, whereas we reported that SPRY2 functions as a putative oncogene in colorectal cancer (CRC) [Oncogene, 2010, 29: 5241–5253]. In general, various studies established inhibition of cell proliferation by SPRY in cancer. The mechanisms by whi...

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Detalles Bibliográficos
Autores principales: Zhang, Qiong, Shim, Katherine, Wright, Kevin, Jurkevich, Alexander, Khare, Sharad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873464/
https://www.ncbi.nlm.nih.gov/pubmed/26293890
http://dx.doi.org/10.1002/mc.22379