Pharmacokinetics of 1-methyl-L-tryptophan after single and repeated subcutaneous application in a porcine model

Increased activity of the tryptophan-metabolizing enzyme indoleamine 2,3-dioxygenase (IDO) is associated with immunological and neurological disorders, and inhibition of its enzyme activity could be a therapeutic approach for treatment of these disorders. The aim of the present study was to establis...

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Detalles Bibliográficos
Autores principales: Wirthgen, Elisa, Kanitz, Ellen, Tuchscherer, Margret, Tuchscherer, Armin, Domanska, Grazyna, Weitschies, Werner, Seidlitz, Anne, Scheuch, Eberhard, Otten, Winfried
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Association for Laboratory Animal Science 2015
Materias:
Original
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873483/
https://www.ncbi.nlm.nih.gov/pubmed/26725587
http://dx.doi.org/10.1538/expanim.15-0096

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873483/
https://www.ncbi.nlm.nih.gov/pubmed/26725587
http://dx.doi.org/10.1538/expanim.15-0096

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