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Pharmacokinetics of 1-methyl-L-tryptophan after single and repeated subcutaneous application in a porcine model

Increased activity of the tryptophan-metabolizing enzyme indoleamine 2,3-dioxygenase (IDO) is associated with immunological and neurological disorders, and inhibition of its enzyme activity could be a therapeutic approach for treatment of these disorders. The aim of the present study was to establis...

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Detalles Bibliográficos
Autores principales:	Wirthgen, Elisa, Kanitz, Ellen, Tuchscherer, Margret, Tuchscherer, Armin, Domanska, Grazyna, Weitschies, Werner, Seidlitz, Anne, Scheuch, Eberhard, Otten, Winfried
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Japanese Association for Laboratory Animal Science 2015
Materias:	Original
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873483/ https://www.ncbi.nlm.nih.gov/pubmed/26725587 http://dx.doi.org/10.1538/expanim.15-0096

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