Toxicogenomic assessment of liver responses following subchronic exposure to furan in Fischer F344 rats

Furan is a widely used industrial chemical and a contaminant in heated foods. Chronic furan exposure causes cholangiocarcinoma and hepatocellular tumors in rats at doses of 2 mg/kg bw/day or greater, with gender differences in frequency and severity. The hepatic transcriptional alterations induced b...

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Detalles Bibliográficos
Autores principales: Dong, Hongyan, Gill, Santokh, Curran, Ivan H., Williams, Andrew, Kuo, Byron, Wade, Michael G., Yauk, Carole L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Toxicogenomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873526/
https://www.ncbi.nlm.nih.gov/pubmed/26194646
http://dx.doi.org/10.1007/s00204-015-1561-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873526/
https://www.ncbi.nlm.nih.gov/pubmed/26194646
http://dx.doi.org/10.1007/s00204-015-1561-2

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