Evaluation of relative effect potencies (REPs) for dioxin-like compounds to derive systemic or human-specific TEFs to improve human risk assessment

Toxic equivalency factors (TEFs) are generally applied for estimating human risk of dioxins and dioxin-like compounds using systemic (e.g., blood) levels, even though these TEFs are established based on intake doses in rodent studies. This review shows that systemic relative effect potencies (REPs)...

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Detalles Bibliográficos
Autores principales: van Ede, Karin I., van Duursen, Majorie B. M., van den Berg, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873528/
https://www.ncbi.nlm.nih.gov/pubmed/27161441
http://dx.doi.org/10.1007/s00204-016-1724-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873528/
https://www.ncbi.nlm.nih.gov/pubmed/27161441
http://dx.doi.org/10.1007/s00204-016-1724-9

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