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High expression of integrin β6 in association with the Rho–Rac pathway identifies a poor prognostic subgroup within HER2 amplified breast cancers

Integrin αvβ6 is involved in the transition from ductal carcinoma in situ (DCIS) to invasive ductal carcinoma (IDC) of the breast. In addition, integrin β6 (ITGB6) is of prognostic value in invasive breast cancers, particularly in HER2+ subtype. However, pathways mediating the activity of integrin α...

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Detalles Bibliográficos
Autores principales: Desai, Krisha, Nair, Madhumathy G., Prabhu, Jyothi S., Vinod, Anupama, Korlimarla, Aruna, Rajarajan, Savitha, Aiyappa, Radhika, Kaluve, Rohini S., Alexander, Annie, Hari, P. S., Mukherjee, Geetashree, Kumar, Rekha V., Manjunath, Suraj, Correa, Marjorrie, Srinath, B. S., Patil, Shekhar, Prasad, M. S. N., Gopinath, K. S., Rao, Raman N., Violette, Shelia M., Weinreb, Paul H., Sridhar, T. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873607/
https://www.ncbi.nlm.nih.gov/pubmed/27184932
http://dx.doi.org/10.1002/cam4.756