Cytoplasmic cyclin D1 regulates cell invasion and metastasis through the phosphorylation of paxillin

Cyclin D1 (Ccnd1) together with its binding partner Cdk4 act as a transcriptional regulator to control cell proliferation and migration, and abnormal Ccnd1·Cdk4 expression promotes tumour growth and metastasis. While different nuclear Ccnd1·Cdk4 targets participating in cell proliferation and tissue...

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Detalles Bibliográficos
Autores principales: Fusté, Noel P., Fernández-Hernández, Rita, Cemeli, Tània, Mirantes, Cristina, Pedraza, Neus, Rafel, Marta, Torres-Rosell, Jordi, Colomina, Neus, Ferrezuelo, Francisco, Dolcet, Xavier, Garí, Eloi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873647/
https://www.ncbi.nlm.nih.gov/pubmed/27181366
http://dx.doi.org/10.1038/ncomms11581

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873647/
https://www.ncbi.nlm.nih.gov/pubmed/27181366
http://dx.doi.org/10.1038/ncomms11581

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