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Cytoplasmic cyclin D1 regulates cell invasion and metastasis through the phosphorylation of paxillin
Cyclin D1 (Ccnd1) together with its binding partner Cdk4 act as a transcriptional regulator to control cell proliferation and migration, and abnormal Ccnd1·Cdk4 expression promotes tumour growth and metastasis. While different nuclear Ccnd1·Cdk4 targets participating in cell proliferation and tissue...
Autores principales: | Fusté, Noel P., Fernández-Hernández, Rita, Cemeli, Tània, Mirantes, Cristina, Pedraza, Neus, Rafel, Marta, Torres-Rosell, Jordi, Colomina, Neus, Ferrezuelo, Francisco, Dolcet, Xavier, Garí, Eloi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873647/ https://www.ncbi.nlm.nih.gov/pubmed/27181366 http://dx.doi.org/10.1038/ncomms11581 |
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