Pseudomonas aeruginosa elastase cleaves a C-terminal peptide from human thrombin that inhibits host inflammatory responses

Pseudomonas aeruginosa is an opportunistic pathogen known for its immune evasive abilities amongst others by degradation of a large variety of host proteins. Here we show that digestion of thrombin by P. aeruginosa elastase leads to the release of the C-terminal thrombin-derived peptide FYT21, which...

Descripción completa

Detalles Bibliográficos
Autores principales: van der Plas, Mariena J. A., Bhongir, Ravi K. V., Kjellström, Sven, Siller, Helena, Kasetty, Gopinath, Mörgelin, Matthias, Schmidtchen, Artur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873665/
https://www.ncbi.nlm.nih.gov/pubmed/27181065
http://dx.doi.org/10.1038/ncomms11567

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873665/
https://www.ncbi.nlm.nih.gov/pubmed/27181065
http://dx.doi.org/10.1038/ncomms11567

Ejemplares similares