Coevolution analysis of Hepatitis C virus genome to identify the structural and functional dependency network of viral proteins

A novel computational approach of coevolution analysis allowed us to reconstruct the protein-protein interaction network of the Hepatitis C Virus (HCV) at the residue resolution. For the first time, coevolution analysis of an entire viral genome was realized, based on a limited set of protein sequen...

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Detalles Bibliográficos
Autores principales: Champeimont, Raphaël, Laine, Elodie, Hu, Shuang-Wei, Penin, Francois, Carbone, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873791/
https://www.ncbi.nlm.nih.gov/pubmed/27198619
http://dx.doi.org/10.1038/srep26401

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873791/
https://www.ncbi.nlm.nih.gov/pubmed/27198619
http://dx.doi.org/10.1038/srep26401

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