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Coevolution analysis of Hepatitis C virus genome to identify the structural and functional dependency network of viral proteins
A novel computational approach of coevolution analysis allowed us to reconstruct the protein-protein interaction network of the Hepatitis C Virus (HCV) at the residue resolution. For the first time, coevolution analysis of an entire viral genome was realized, based on a limited set of protein sequen...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873791/ https://www.ncbi.nlm.nih.gov/pubmed/27198619 http://dx.doi.org/10.1038/srep26401 |