Fly DPP10 acts as a channel ancillary subunit and possesses peptidase activity

Mammalian DPP6 (DPPX) and DPP10 (DPPY) belong to a family of dipeptidyl peptidases, but lack enzyme activity. Instead, these proteins form complexes with voltage-gated K(+) channels in Kv4 family to control their gating and other properties. Here, we find that the fly DPP10 ortholog acts as an ancil...

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Detalles Bibliográficos
Autores principales: Shiina, Yohei, Muto, Tomohiro, Zhang, Zhili, Baihaqie, Ahmad, Yoshizawa, Takamasa, Lee, Hye-in J., Park, Eulsoon, Tsukiji, Shinya, Takimoto, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873792/
https://www.ncbi.nlm.nih.gov/pubmed/27198182
http://dx.doi.org/10.1038/srep26290

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873792/
https://www.ncbi.nlm.nih.gov/pubmed/27198182
http://dx.doi.org/10.1038/srep26290

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