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PKA-CREB-BDNF signaling regulated long lasting antidepressant activities of Yueju but not ketamine
Yueju confers antidepressant effects in a rapid and long-lasting manner, similar to ketamine. CREB (cAMP-response element binding protein) signaling is implicated in depression pathology and antidepressant responses. However, the role of CREB and associated brain derived neurotrophic factor (BDNF) s...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873804/ https://www.ncbi.nlm.nih.gov/pubmed/27197752 http://dx.doi.org/10.1038/srep26331 |