Imaging Tumor Vascularity and Response to Anti-Angiogenic Therapy Using Gaussia Luciferase

We developed a novel approach to assess tumor vascularity using recombinant Gaussia luciferase (rGluc) protein and bioluminescence imaging. Upon intravenous injection of rGluc followed by its substrate coelenterazine, non-invasive visualization of tumor vascularity by bioluminescence imaging was pos...

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Detalles Bibliográficos
Autores principales: Kantar, Rami S., Lashgari, Ghazal, Tabet, Elie I., Lewandrowski, Grant K., Carvalho, Litia A., Tannous, Bakhos A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873808/
https://www.ncbi.nlm.nih.gov/pubmed/27198044
http://dx.doi.org/10.1038/srep26353

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873808/
https://www.ncbi.nlm.nih.gov/pubmed/27198044
http://dx.doi.org/10.1038/srep26353

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