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Imaging Tumor Vascularity and Response to Anti-Angiogenic Therapy Using Gaussia Luciferase
We developed a novel approach to assess tumor vascularity using recombinant Gaussia luciferase (rGluc) protein and bioluminescence imaging. Upon intravenous injection of rGluc followed by its substrate coelenterazine, non-invasive visualization of tumor vascularity by bioluminescence imaging was pos...
Autores principales: | Kantar, Rami S., Lashgari, Ghazal, Tabet, Elie I., Lewandrowski, Grant K., Carvalho, Litia A., Tannous, Bakhos A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873808/ https://www.ncbi.nlm.nih.gov/pubmed/27198044 http://dx.doi.org/10.1038/srep26353 |
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