Persistence of Plasmodium falciparum parasitemia after artemisinin combination therapy: evidence from a randomized trial in Uganda

Artemisinin resistance is rapidly spreading in Southeast Asia. The efficacy of artemisinin-combination therapy (ACT) continues to be excellent across Africa. We performed parasite transcriptional profiling and genotyping on samples from an antimalarial treatment trial in Uganda. We used qRT-PCR and...

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Detalles Bibliográficos
Autores principales: Chang, Hsiao-Han, Meibalan, Elamaran, Zelin, Justin, Daniels, Rachel, Eziefula, Alice C., Meyer, Evan C., Tadesse, Fitsum, Grignard, Lynn, Joice, Regina C., Drakeley, Chris, Wirth, Dyann F., Volkman, Sarah K., Buckee, Caroline, Bousema, Teun, Marti, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873826/
https://www.ncbi.nlm.nih.gov/pubmed/27197604
http://dx.doi.org/10.1038/srep26330

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873826/
https://www.ncbi.nlm.nih.gov/pubmed/27197604
http://dx.doi.org/10.1038/srep26330

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