Experimental priming of encephalitogenic Th1/Th17 cells requires pertussis toxin-driven IL-1β production by myeloid cells

CD4(+) Th17 are heterogeneous in terms of cytokine production and capacity to initiate autoimmune diseases, such as experimental autoimmune encephalomyelitis (EAE). Here we demonstrate that experimental priming of encephalitogenic Th cells expressing RORγt and T-bet and producing IL-17A, IFN-γ and G...

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Detalles Bibliográficos
Autores principales: Ronchi, Francesca, Basso, Camilla, Preite, Silvia, Reboldi, Andrea, Baumjohann, Dirk, Perlini, Luana, Lanzavecchia, Antonio, Sallusto, Federica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873938/
https://www.ncbi.nlm.nih.gov/pubmed/27189410
http://dx.doi.org/10.1038/ncomms11541

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873938/
https://www.ncbi.nlm.nih.gov/pubmed/27189410
http://dx.doi.org/10.1038/ncomms11541

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