Context-dependent switch in chemo/mechanotransduction via multilevel crosstalk among cytoskeleton-regulated MRTF and TAZ and TGFβ-regulated Smad3

Myocardin-related transcription factor (MRTF) and TAZ are major mechanosensitive transcriptional co-activators that link cytoskeleton organization to gene expression. Despite many similarities in their regulation, their physical and/or functional interactions are unknown. Here we show that MRTF and...

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Detalles Bibliográficos
Autores principales: Speight, Pam, Kofler, Michael, Szászi, Katalin, Kapus, András
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873981/
https://www.ncbi.nlm.nih.gov/pubmed/27189435
http://dx.doi.org/10.1038/ncomms11642

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873981/
https://www.ncbi.nlm.nih.gov/pubmed/27189435
http://dx.doi.org/10.1038/ncomms11642

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