Blood coagulation factor XII drives adaptive immunity during neuroinflammation via CD87-mediated modulation of dendritic cells

Aberrant immune responses represent the underlying cause of central nervous system (CNS) autoimmunity, including multiple sclerosis (MS). Recent evidence implicated the crosstalk between coagulation and immunity in CNS autoimmunity. Here we identify coagulation factor XII (FXII), the initiator of th...

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Detalles Bibliográficos
Autores principales: Göbel, Kerstin, Pankratz, Susann, Asaridou, Chloi-Magdalini, Herrmann, Alexander M., Bittner, Stefan, Merker, Monika, Ruck, Tobias, Glumm, Sarah, Langhauser, Friederike, Kraft, Peter, Krug, Thorsten F., Breuer, Johanna, Herold, Martin, Gross, Catharina C., Beckmann, Denise, Korb-Pap, Adelheid, Schuhmann, Michael K., Kuerten, Stefanie, Mitroulis, Ioannis, Ruppert, Clemens, Nolte, Marc W., Panousis, Con, Klotz, Luisa, Kehrel, Beate, Korn, Thomas, Langer, Harald F., Pap, Thomas, Nieswandt, Bernhard, Wiendl, Heinz, Chavakis, Triantafyllos, Kleinschnitz, Christoph, Meuth, Sven G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873982/
https://www.ncbi.nlm.nih.gov/pubmed/27188843
http://dx.doi.org/10.1038/ncomms11626

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873982/
https://www.ncbi.nlm.nih.gov/pubmed/27188843
http://dx.doi.org/10.1038/ncomms11626

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