Inference of kinship using spatial distributions of SNPs for genome-wide association studies

BACKGROUND: Genome-wide association studies (GWASs) are powerful in identifying genetic loci which cause complex traits of common diseases. However, it is well known that inappropriately accounting for pedigree or population structure leads to spurious associations. GWASs have often encountered incr...

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Detalles Bibliográficos
Autores principales: Lee, Hyokyeong, Chen, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873983/
https://www.ncbi.nlm.nih.gov/pubmed/27206321
http://dx.doi.org/10.1186/s12864-016-2696-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873983/
https://www.ncbi.nlm.nih.gov/pubmed/27206321
http://dx.doi.org/10.1186/s12864-016-2696-0

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