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Inference of kinship using spatial distributions of SNPs for genome-wide association studies
BACKGROUND: Genome-wide association studies (GWASs) are powerful in identifying genetic loci which cause complex traits of common diseases. However, it is well known that inappropriately accounting for pedigree or population structure leads to spurious associations. GWASs have often encountered incr...
Autores principales: | Lee, Hyokyeong, Chen, Liang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873983/ https://www.ncbi.nlm.nih.gov/pubmed/27206321 http://dx.doi.org/10.1186/s12864-016-2696-0 |
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