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Low WT1 transcript levels at diagnosis predicted poor outcomes of acute myeloid leukemia patients with t(8;21) who received chemotherapy or allogeneic hematopoietic stem cell transplantation

BACKGROUND: Acute myeloid leukemia (AML) with t(8;21) is a heterogeneous disease. Identifying AML patients with t(8;21) who have a poor prognosis despite achieving remission is important for determining the best subsequent therapy. This study aimed to evaluate the impact of Wilm tumor gene-1 (WT1) t...

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Detalles Bibliográficos
Autores principales: Qin, Ya-Zhen, Wang, Yu, Zhu, Hong-Hu, Gale, Robert Peter, Zhang, Mei-Jie, Jiang, Qian, Jiang, Hao, Xu, Lan-Ping, Chen, Huan, Zhang, Xiao-Hui, Liu, Yan-Rong, Lai, Yue-Yun, Jiang, Bin, Liu, Kai-Yan, Huang, Xiao-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873994/
https://www.ncbi.nlm.nih.gov/pubmed/27197573
http://dx.doi.org/10.1186/s40880-016-0110-6