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Differential Lyn-dependence of the SHIP1-deficient mast cell phenotype

BACKGROUND: Antigen (Ag)/IgE-mediated mast cell (MC) responses play detrimental roles in allergic diseases. MC activation via the high-affinity receptor for IgE (FcεRI) is controlled by the Src family kinase Lyn. Lyn-deficient (-/-) bone marrow-derived MCs (BMMCs) have been shown by various laborato...

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Detalles Bibliográficos
Autores principales:	Nunes de Miranda, Susana M., Wilhelm, Thomas, Huber, Michael, Zorn, Carolin N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4874025/ https://www.ncbi.nlm.nih.gov/pubmed/27206658 http://dx.doi.org/10.1186/s12964-016-0135-0

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