Virtual Dual inhibition of COX-2 / 5-LOX enzymes based on binding properties of alpha-amyrins, the anti-inflammatory compound as a promising anti-cancer drug

Hydro-alcoholic fruit extract of Cordia myxa was considerably effective on curing acute inflammation in mouse model. Previous studies suggested significant anti-inflammatory activities as well as potential anticancer agent of α-amyrins in seeds. Inhibition of Cyclooxygenase-2 (COX-2) and 5-Lipooxyge...

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Detalles Bibliográficos
Autores principales: Ranjbar, Mohammad Mehdi, Assadolahi, Vahideh, Yazdani, Mohsen, Nikaein, Donya, Rashidieh, Behnam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Leibniz Research Centre for Working Environment and Human Factors 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4874318/
https://www.ncbi.nlm.nih.gov/pubmed/27231478
http://dx.doi.org/10.17179/excli2016-164

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4874318/
https://www.ncbi.nlm.nih.gov/pubmed/27231478
http://dx.doi.org/10.17179/excli2016-164

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