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Survival of glucose phosphate isomerase null somatic cells and germ cells in adult mouse chimaeras

The mouse Gpi1 gene encodes the glycolytic enzyme glucose phosphate isomerase. Homozygous Gpi1(−/−) null mouse embryos die but a previous study showed that some homozygous Gpi1(−/−) null cells survived when combined with wild-type cells in fetal chimaeras. One adult female Gpi1(−/−)↔Gpi1(c/c) chimae...

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Detalles Bibliográficos
Autores principales: Keighren, Margaret A., Flockhart, Jean H., West, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4874354/
https://www.ncbi.nlm.nih.gov/pubmed/27103217
http://dx.doi.org/10.1242/bio.017111