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Survival of glucose phosphate isomerase null somatic cells and germ cells in adult mouse chimaeras
The mouse Gpi1 gene encodes the glycolytic enzyme glucose phosphate isomerase. Homozygous Gpi1(−/−) null mouse embryos die but a previous study showed that some homozygous Gpi1(−/−) null cells survived when combined with wild-type cells in fetal chimaeras. One adult female Gpi1(−/−)↔Gpi1(c/c) chimae...
Autores principales: | Keighren, Margaret A., Flockhart, Jean H., West, John D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4874354/ https://www.ncbi.nlm.nih.gov/pubmed/27103217 http://dx.doi.org/10.1242/bio.017111 |
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