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CLIC1 regulates dendritic cell antigen processing and presentation by modulating phagosome acidification and proteolysis

Intracellular chloride channel protein 1 (CLIC1) participates in inflammatory processes by regulating macrophage phagosomal functions such as pH and proteolysis. Here, we sought to determine if CLIC1 can regulate adaptive immunity by actions on dendritic cells (DCs), the key professional antigen pre...

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Detalles Bibliográficos
Autores principales: Salao, Kanin, Jiang, Lele, Li, Hui, Tsai, Vicky W.-W., Husaini, Yasmin, Curmi, Paul M. G., Brown, Louise J., Brown, David A., Breit, Samuel N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4874360/
https://www.ncbi.nlm.nih.gov/pubmed/27113959
http://dx.doi.org/10.1242/bio.018119