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CLIC1 regulates dendritic cell antigen processing and presentation by modulating phagosome acidification and proteolysis
Intracellular chloride channel protein 1 (CLIC1) participates in inflammatory processes by regulating macrophage phagosomal functions such as pH and proteolysis. Here, we sought to determine if CLIC1 can regulate adaptive immunity by actions on dendritic cells (DCs), the key professional antigen pre...
Autores principales: | Salao, Kanin, Jiang, Lele, Li, Hui, Tsai, Vicky W.-W., Husaini, Yasmin, Curmi, Paul M. G., Brown, Louise J., Brown, David A., Breit, Samuel N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4874360/ https://www.ncbi.nlm.nih.gov/pubmed/27113959 http://dx.doi.org/10.1242/bio.018119 |
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