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A Graph Based Framework to Model Virus Integration Sites

With next generation sequencing thousands of virus and viral vector integration genome targets are now under investigation to uncover specific integration preferences and to define clusters of integration, termed common integration sites (CIS), that may allow to assess gene therapy safety or to dete...

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Detalles Bibliográficos
Autores principales: Fronza, Raffaele, Vasciaveo, Alessandro, Benso, Alfredo, Schmidt, Manfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4874582/
https://www.ncbi.nlm.nih.gov/pubmed/27257470
http://dx.doi.org/10.1016/j.csbj.2015.10.006