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DEFB1 gene polymorphisms and tuberculosis in a Northeastern Brazilian population

β-Defensin-1, an antimicrobial peptide encoded by the DEFB1 gene, is known to play an important role in lung mucosal immunity. In our association study we analyzed three DEFB1 functional polymorphisms −52G>A (rs1799946), −44C>G (rs1800972) and −20G>A (rs11362) in 92 tuberculosis patients an...

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Detalles Bibliográficos
Autores principales: Celerino da Silva, Ronaldo, da Cruz, Heidi Lacerda Alves, Brandão, Lucas André Cavalcanti, Guimarães, Rafael Lima, Montenegro, Lilian Maria Lapa, Schindler, Haiana Charifker, Segat, Ludovica, Crovella, Sergio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4874611/
https://www.ncbi.nlm.nih.gov/pubmed/26991287
http://dx.doi.org/10.1016/j.bjm.2015.09.001