Zinc Finger Domain of the PRDM9 Gene on Chromosome 1 Exhibits High Diversity in Ruminants but Its Paralog PRDM7 Contains Multiple Disruptive Mutations

PRDM9 is the sole hybrid sterility gene identified so far in vertebrates. PRDM9 gene encodes a protein with an immensely variable zinc-finger (ZF) domain that determines the site of meiotic recombination hotspots genome-wide. In this study, the terminal ZF domain of PRDM9 on bovine chromosome 1 and...

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Detalles Bibliográficos
Autores principales: Ahlawat, Sonika, Sharma, Priyanka, Sharma, Rekha, Arora, Reena, De, Sachinandan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4874674/
https://www.ncbi.nlm.nih.gov/pubmed/27203728
http://dx.doi.org/10.1371/journal.pone.0156159

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4874674/
https://www.ncbi.nlm.nih.gov/pubmed/27203728
http://dx.doi.org/10.1371/journal.pone.0156159

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