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Computational Identification of Genomic Features That Influence 3D Chromatin Domain Formation
Recent advances in long-range Hi-C contact mapping have revealed the importance of the 3D structure of chromosomes in gene expression. A current challenge is to identify the key molecular drivers of this 3D structure. Several genomic features, such as architectural proteins and functional elements,...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4874696/ https://www.ncbi.nlm.nih.gov/pubmed/27203237 http://dx.doi.org/10.1371/journal.pcbi.1004908 |