Cargando…

Epistasis between antibiotic resistance mutations and genetic background shape the fitness effect of resistance across species of Pseudomonas

Antibiotic resistance often evolves by mutations at conserved sites in essential genes, resulting in parallel molecular evolution between divergent bacterial strains and species. Whether these resistance mutations are having parallel effects on fitness across bacterial taxa, however, is unclear. Thi...

Descripción completa

Detalles Bibliográficos
Autores principales: Vogwill, T., Kojadinovic, M., MacLean, R. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4874708/
https://www.ncbi.nlm.nih.gov/pubmed/27170722
http://dx.doi.org/10.1098/rspb.2016.0151