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Epistasis between antibiotic resistance mutations and genetic background shape the fitness effect of resistance across species of Pseudomonas
Antibiotic resistance often evolves by mutations at conserved sites in essential genes, resulting in parallel molecular evolution between divergent bacterial strains and species. Whether these resistance mutations are having parallel effects on fitness across bacterial taxa, however, is unclear. Thi...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4874708/ https://www.ncbi.nlm.nih.gov/pubmed/27170722 http://dx.doi.org/10.1098/rspb.2016.0151 |