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A physical model describing the interaction of nuclear transport receptors with FG nucleoporin domain assemblies

The permeability barrier of nuclear pore complexes (NPCs) controls bulk nucleocytoplasmic exchange. It consists of nucleoporin domains rich in phenylalanine-glycine motifs (FG domains). As a bottom-up nanoscale model for the permeability barrier, we have used planar films produced with three differe...

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Detalles Bibliográficos
Autores principales: Zahn, Raphael, Osmanović, Dino, Ehret, Severin, Araya Callis, Carolina, Frey, Steffen, Stewart, Murray, You, Changjiang, Görlich, Dirk, Hoogenboom, Bart W, Richter, Ralf P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4874776/
https://www.ncbi.nlm.nih.gov/pubmed/27058170
http://dx.doi.org/10.7554/eLife.14119